DegronMD - P04217(A1BG)

GO - Biological processes (BP):

GO - Molecular function (MF):

GO - Cellular component (CC): blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lu... View more >>

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Degron hit	Class	E3 ligase	Source protein	Location	Detail
DHEFLEVPEA	DEG_COP1_1	COP1	Alpha-1B-glycoprotein	155:164	More..

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P162L	TCGA-86-A4JF	LUAD	TCGA	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation altering degron motif	0.7582
p.P162L	DO45317	LUAD	ICGC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation altering degron motif	0.7582
p.H156N	DO23484	LINC	ICGC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation altering degron motif	0.6312
p.R152Q	TCGA-25-2042	OV	TCGA	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.25
p.R152Q	DO28249	OV	ICGC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.25
p.R152L	DO50786	LICA	ICGC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.25
p.A170V	SIDM01112	Osteosarcoma	GDSC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.1667
p.A170V	SIDM00793	Burkitt's Lymphoma	GDSC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.1667
p.A170V	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	DHEFLEVPEA	DEG_COP1_1	155:164	Mutation rewiring degron network	0.1667

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No resistance data available for this Degron.

Kaplan plot for A1BG in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

A1BG

UniProt ID: P04217

Entrez ID: 1

Protein name: Alpha-1B-glycoprotein (Alpha-1-B glycoprotein)

External links: UniprotKB HGNC RefSeq COSMIC

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No resistance data available for this Degron.

Kaplan plot for A1BG in