DegronMD - P05091(ALDH2)

ALDH2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T56A	TCGA-BR-8591	STAD	TCGA	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.2778
p.T56A	DO47973	STAD	ICGC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.2778
p.A48S	DO229028	LICA	ICGC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.0556
p.R51K	SIDM00175	Melanoma	GDSC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.1389
p.R51K	ACH-002096	Skin Cancer	CCLE	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.1389
p.R51K	CP50-MEL-B	skin	COSMIC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.1389
p.A48V	SIDM00534	Colorectal Carcinoma	GDSC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.0556
p.A48V	ACH-000986	Colon/Colorectal Cancer	CCLE	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.0556
p.A48V	HT-115	large intestine	COSMIC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.0556
p.G71R	SIDM01617	Endometrial Carcinoma	GDSC	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.1111
p.G71R	ACH-000994	Endometrial/Uterine Cancer	CCLE	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.1111
p.T56I	ACH-000954	Endometrial/Uterine Cancer	CCLE	NPSTGE	DEG_Kelch_Keap1_1	58:63	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc