CRH
UniProt ID: P06850
Entrez ID: 1392
Protein name: Corticoliberin (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {ECO:0000250|UniProtKB:P06296, ECO:0000250|UniProtKB:Q8CIT0}....
FUNCTION: Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {ECO:0000250|UniProtKB:P06296, ECO:0000250|UniProtKB:Q8CIT0}.
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GO - Biological processes (BP):
adrenal gland development [GO:0030325]; chemical synaptic transmission [GO:0007268]; female pregnancy [GO:0007565]; glucocorticoid biosynthetic process [GO:0006704]; inflammatory response [GO:0006954]; learning or memory [GO:0007611]; locomotory exploration behavior [GO:0035641]; lung development [G...
adrenal gland development [GO:0030325]; chemical synaptic transmission [GO:0007268]; female pregnancy [GO:0007565]; glucocorticoid biosynthetic process [GO:0006704]; inflammatory response [GO:0006954]; learning or memory [GO:0007611]; locomotory exploration behavior [GO:0035641]; lung development [GO:0030324]; negative regulation of circadian sleep/wake cycle, REM sleep [GO:0042322]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of glucagon secretion [GO:0070093]; parturition [GO:0007567]; positive regulation of circadian sleep/wake cycle, wakefulness [GO:0010841]; positive regulation of corticotropin secretion [GO:0051461]; positive regulation of cortisol secretion [GO:0051464]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, dopaminergic [GO:0001963]
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GO - Molecular function (MF):
corticotropin-releasing hormone activity [GO:0017045]; hormone activity [GO:0005179]; neuropeptide hormone activity [GO:0005184]; signaling receptor binding [GO:0005102]...
corticotropin-releasing hormone activity [GO:0017045]; hormone activity [GO:0005179]; neuropeptide hormone activity [GO:0005184]; signaling receptor binding [GO:0005102]
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GO - Cellular component (CC):
extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; synapse [GO:0045202]...
extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; synapse [GO:0045202]
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CRH
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Kaplan plot for CRH in
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*NOTE: the Kaplan plots were collected from OncoLnc