DegronMD - P06865(HEXA)

HEXA

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W266G	TCGA-B2-4098	KIRC	TCGA	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.1389
p.T286A	TCGA-CV-5973	HNSC	TCGA	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.1389
p.C277Y	TCGA-MX-A663	STAD	TCGA	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation altering degron motif	0.5976
p.E274Q	DO2401	BRCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation altering degron motif	0.6744
p.I263V	DO229010	COCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.0556
p.I263V	DO229013	COCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.0556
p.I263V	DO229016	COCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.0556
p.I263V	DO229003	COCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.0556
p.I263V	DO229005	COCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.0556
p.G271S	DO23561	LUAD	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation rewiring degron network	0.2778
p.P273T	DO39552	THCA	ICGC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation altering degron motif	0.7031
p.S279C	CHSA8926	bone	COSMIC	LLTPCYS	DEG_SCF_FBW7_1	273:279	Mutation altering degron motif	0.7541

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*NOTE: the Kaplan plots were collected from OncoLnc