DegronMD - P07332(FES)

FES

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S60R	TCGA-AP-A051	UCEC	TCGA	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation altering degron motif	0.7427
p.S60R	DO42673	UCEC	ICGC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation altering degron motif	0.7427
p.M51T	TCGA-DI-A1BU	UCEC	TCGA	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.2222
p.M51T	DO42023	UCEC	ICGC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.2222
p.S67I	DO222454	BTCA	ICGC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation blocking phosphorylation signal	0.5833
p.A62T	DO234389	ESAD	ICGC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.2778
p.R61Q	SIDM00332	Breast Carcinoma	GDSC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.3056
p.R61Q	ACH-001819	Breast Cancer	CCLE	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.3056
p.R61Q	MFM-223	breast	COSMIC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation rewiring degron network	0.3056
p.G58S	SIDM00618	Hepatocellular Carcinoma	GDSC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation altering degron motif	0.5882
p.G58S	ACH-000620	Liver Cancer	CCLE	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation altering degron motif	0.5882
p.G58S	JHH-1	liver	COSMIC	DSGGQS	DEG_SCF_TRCP1_1	55:60	Mutation altering degron motif	0.5882

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*NOTE: the Kaplan plots were collected from OncoLnc