DegronMD - P0CG40(SP9)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G449S	TCGA-CK-6747	COAD	TCGA	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation rewiring degron network	0.0556
p.G449S	DO10156	COAD	ICGC	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation rewiring degron network	0.0556
p.R437H	DO10140	COAD	ICGC	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation altering degron motif	0.7133
p.D425N	DO234197	ESAD	ICGC	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation rewiring degron network	0.1111
p.G423D	DO233634	GACA	ICGC	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation rewiring degron network	0.0556
p.S440P	DO228901	LICA	ICGC	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation blocking phosphorylation signal	0.75
p.L433P	ACH-001786	Colon/Colorectal Cancer	CCLE	LETPRSE	DEG_SCF_FBW7_2	433:439	Mutation altering degron motif	0.6471

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons