DegronMD - P0CJ72(MTRNR2L5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T13S	DO225249	BRCA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO229013	COCA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO229003	COCA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO229005	COCA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO234285	ESAD	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO230659	LAML	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.T13I	DO230929	LUSC	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.S12L	DO229030	LICA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1944
p.D17E	DO230979	LUSC	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.0556
p.D17E	DO224610	LUSC	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.0556
p.E15K	DO222644	MELA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1111
p.E15K	DO218846	SKCA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1111
p.E15K	DO37782	SKCM	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1111
p.G5V	DO46909	RECA	ICGC	MATPGFS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.6421

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons