DegronMD - P10696(ALPG)

ALPG

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G220V	SIDM00094	Kidney Carcinoma	GDSC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation rewiring degron network	0.1111
p.G220V	SN12C	kidney	COSMIC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation rewiring degron network	0.1111
p.E235K	SIDM00920	Breast Carcinoma	GDSC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.7022
p.E235K	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.7022
p.E235K	CAMA-1	breast	COSMIC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.7022
p.E235K	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.7022
p.P232S	SIDM00068	Colorectal Carcinoma	GDSC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.6752
p.P232S	GEO	large intestine	COSMIC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation altering degron motif	0.6752
p.G243S	Sarc9371	bone	COSMIC	PMGTPDPE	DEG_SCF_FBW7_2	228:235	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc