DegronMD - P10966(CD8B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N19S	TCGA-49-AARE	LUAD	TCGA	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.0556
p.N19S	DO218922	LUAD	ICGC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.0556
p.L16I	TCGA-B5-A3FC	UCEC	TCGA	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1389
p.L16I	DO41871	UCEC	ICGC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1389
p.L16F	TCGA-BF-A5EO	SKCM	TCGA	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1389
p.L16F	DO219450	SKCM	ICGC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1389
p.R2W	DO232761	PBCA	ICGC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation altering degron motif	0.8634
p.H17Q	SIDM00286	Neuroblastoma	GDSC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1111
p.H17Q	SIDM01134	Small Cell Lung Carcinoma	GDSC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1111
p.H17Q	SIDM00833	Colorectal Carcinoma	GDSC	MRPRLWLLL	DEG_APCC_DBOX_1	1:9	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons