DegronMD - P11168(SLC2A2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A88E	TCGA-37-4130	LUSC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1944
p.A88E	DO229018	LICA	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1944
p.A88E	DO26490	LUSC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1944
p.S71L	TCGA-43-5670	LUSC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1944
p.S71L	DO26434	LUSC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1944
p.S73T	TCGA-49-AARE	LUAD	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.25
p.S73T	DO218922	LUAD	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.25
p.N75K	TCGA-A5-A0G1	UCEC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.3056
p.N75K	DO42472	UCEC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.3056
p.N75K	SIDM00683	Prostate Carcinoma	GDSC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.3056
p.N75K	ACH-000977	lymph node	CCLE	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.3056
p.N75K	LNCaP-Clone-FGC	prostate	COSMIC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.3056
p.K77Q	TCGA-B5-A11H	UCEC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation altering degron motif	0.5833
p.K77Q	DO42825	UCEC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation altering degron motif	0.5833
p.E85D	TCGA-D1-A16X	UCEC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2778
p.E85D	TCGA-VS-A8EJ	CESC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2778
p.E85D	DO51622	CESC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2778
p.E85D	DO41799	UCEC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2778
p.L92V	TCGA-DD-AAEI	LIHC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.0833
p.L92V	DO219575	LIHC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.0833
p.I70L	TCGA-ES-A2HT	LIHC	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1667
p.I70L	DO22956	LIHC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1667
p.E83K	TCGA-IG-A5B8	ESCA	TCGA	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation altering degron motif	0.7022
p.I70V	DO222947	BTCA	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1667
p.I70V	SIDM01554	Mesothelioma	GDSC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1667
p.I70V	ACH-000331	Lung Cancer	CCLE	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1667
p.Q91K	DO229027	LICA	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.1111
p.E85Q	DO224563	LUSC	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2778
p.E66K	DO222710	MELA	ICGC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.0556
p.Y72H	SIDM00449	B-Lymphoblastic Leukemia	GDSC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2222
p.Y72H	ACH-000922	Leukemia	CCLE	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2222
p.Y72H	RCH-ACV	haematopoietic and lymphoid tissue	COSMIC	PKPTPWAE	DEG_SCF_FBW7_2	76:83	Mutation rewiring degron network	0.2222

Kaplan plot for SLC2A2 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SLC2A2

UniProt ID: P11168

Entrez ID: 6514

Protein name: Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for SLC2A2 in