DegronMD - P11498(PC)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S424P	TCGA-AP-A059	UCEC	TCGA	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.3056
p.D408Y	TCGA-D3-A8GB	SKCM	TCGA	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0556
p.R413Q	DO47537	SKCM	ICGC	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1944
p.G414C	DO40801	UCEC	ICGC	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.2222
p.A412T	SIDM01307	Colorectal Carcinoma	GDSC	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.1667
p.G433D	SIDM01609	Endometrial Carcinoma	GDSC	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0556
p.G433D	ACH-000972	Endometrial/Uterine Cancer	CCLE	ISPHYD	LIG_APCC_ABBA_1	418:423	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons