DegronMD - P11836(MS4A1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T2K	TCGA-13-0726	OV	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7306
p.T2K	DO28373	OV	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.7306
p.T11N	TCGA-44-2657	LUAD	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation blocking phosphorylation signal	0.6667
p.T11N	TCGA-F5-6814	READ	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation blocking phosphorylation signal	0.6667
p.T11N	DO25020	LUAD	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation blocking phosphorylation signal	0.6667
p.T11N	DO36556	READ	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation blocking phosphorylation signal	0.6667
p.E15K	TCGA-66-2773	LUSC	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1111
p.E15K	DO26536	LUSC	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1111
p.N6I	TCGA-94-8491	LUSC	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.6169
p.N6I	DO219174	LUSC	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation altering degron motif	0.6169
p.G10W	TCGA-D3-A2JD	SKCM	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.25
p.G10W	DO37543	SKCM	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.25
p.G10R	TCGA-DK-A1A3	BLCA	TCGA	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.25
p.G10R	DO558	BLCA	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.25
p.P13L	DO233271	GACA	ICGC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.P13L	SIDM00845	Burkitt's Lymphoma	GDSC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667
p.P13L	SIDM00154	Mesothelioma	GDSC	MTTPRNS	DEG_SCF_FBW7_1	1:7	Mutation rewiring degron network	0.1667

Kaplan plot for MS4A1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MS4A1

UniProt ID: P11836

Entrez ID: 931

Protein name: B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MS4A1 in