DegronMD - P12034(FGF5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q48P	TCGA-22-4613	LUSC	TCGA	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1944
p.Q48P	DO26468	LUSC	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1944
p.P63A	TCGA-62-A46O	LUAD	TCGA	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1667
p.P63A	DO26240	LUAD	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1667
p.S49I	TCGA-A5-A0G2	UCEC	TCGA	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.2222
p.S49I	DO41235	UCEC	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.2222
p.S44P	TCGA-A5-A0VP	UCEC	TCGA	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.0833
p.S44P	DO42600	UCEC	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.0833
p.A53T	TCGA-AX-A0J1	UCEC	TCGA	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.7139
p.A53T	DO233823	GACA	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.7139
p.A53T	DO41199	UCEC	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.7139
p.A59T	DO233737	GACA	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.2778
p.S52N	DO232761	PBCA	ICGC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.3056
p.M54V	SIDM00845	Burkitt's Lymphoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01090	Colorectal Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00967	Ovarian Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01126	Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00633	Breast Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00654	Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00447	B-Lymphoblastic Leukemia	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00529	Breast Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00875	Breast Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00032	Bladder Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01147	Gastric Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00793	Burkitt's Lymphoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01133	Other Solid Cancers	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00068	Colorectal Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00721	Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00720	Mesothelioma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM00808	Burkitt's Lymphoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01387	Small Cell Lung Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01763	Rhabdomyosarcoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01254	Burkitt's Lymphoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.M54V	SIDM01525	Acute Myeloid Leukemia	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6097
p.L67P	SIDM00845	Burkitt's Lymphoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.0556
p.M54I	SIDM00660	Colorectal Carcinoma	GDSC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6507
p.M54I	ACH-000985	Colon/Colorectal Cancer	CCLE	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6507
p.M54I	LS-411N	large intestine	COSMIC	AMSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6507

Kaplan plot for FGF5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FGF5

UniProt ID: P12034

Entrez ID: 2250

Protein name: Fibroblast growth factor 5 (FGF-5) (Heparin-binding growth factor 5) (HBGF-5) (Smag-82)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FGF5 in