DegronMD - P12524(MYCL)

MYCL

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E133Q	TCGA-AD-A5EJ	COAD	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.6744
p.E133Q	DO50090	COAD	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.6744
p.S140N	TCGA-BA-5151	HNSC	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.2222
p.S140N	DO14276	HNSC	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.2222
p.A144S	TCGA-CD-5813	STAD	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.1111
p.A144S	DO38259	STAD	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.1111
p.E133K	TCGA-E6-A1LX	UCEC	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.7022
p.E133K	TCGA-UZ-A9PS	KIRP	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.7022
p.E133K	DO219709	KIRP	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.7022
p.E133K	DO41020	UCEC	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation altering degron motif	0.7022
p.L143I	TCGA-EY-A1GO	UCEC	TCGA	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.1389
p.L143I	DO41392	UCEC	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.1389
p.G128D	DO228957	LICA	ICGC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.3056
p.P123L	LIM1215	large intestine	COSMIC	PDCTPSLE	DEG_SCF_FBW7_2	129:136	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc