DegronMD - P13378(HOXD8)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D259G	TCGA-AA-3510	COAD	TCGA	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.2778
p.F261C	TCGA-AA-A010	COAD	TCGA	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.2222
p.F261C	TCGA-B5-A11N	UCEC	TCGA	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.2222
p.D259E	TCGA-OR-A5KB	ACC	TCGA	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.2778
p.D258G	DO7783	COAD	ICGC	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.3056
p.F260C	DO41458	UCEC	ICGC	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation substituting flanking lysine	0.3611
p.P262L	SIDM00763	Non-Small Cell Lung Carcinoma	GDSC	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.1944
p.P262L	NCI-H1915	lung	COSMIC	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.1944
p.P261L	NCI-H1915	lung	COSMIC	KKENN	DEG_APCC_KENBOX_2	253:257	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons