DegronMD - P13497(BMP1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T780S	TCGA-24-2290	OV	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.25
p.T780S	DO30090	OV	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.25
p.R784W	TCGA-AA-3663	COAD	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation altering degron motif	0.8634
p.R784W	DO9346	COAD	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation altering degron motif	0.8634
p.R784W	DO227646	COCA	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation altering degron motif	0.8634
p.Q797H	TCGA-AP-A059	UCEC	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1667
p.Q797H	DO41361	UCEC	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1667
p.G782R	TCGA-BK-A13B	UCEC	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.3056
p.G782R	DO227976	COCA	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.3056
p.G782R	DO40825	UCEC	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.3056
p.S778Y	TCGA-ER-A19P	SKCM	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1944
p.S778Y	DO47623	SKCM	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1944
p.R784L	TCGA-OR-A5JA	ACC	TCGA	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation altering degron motif	0.8428
p.R801T	DO6269	CESC	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.0556
p.S778A	DO222798	COCA	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1944
p.K799N	DO229027	LICA	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.1111
p.Q773E	DO45444	LUSC	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation rewiring degron network	0.0556
p.W791L	DO47578	SKCM	ICGC	HRVKLTFME	DEG_APCC_DBOX_1	783:791	Mutation altering degron motif	0.7015

Kaplan plot for BMP1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BMP1

UniProt ID: P13497

Entrez ID: 649

Protein name: Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for BMP1 in