ATP1A3
UniProt ID: P13637
Entrez ID: 478
Protein name: Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active tran...
FUNCTION: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
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GO - Biological processes (BP):
cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular potassium ion homeostasis [GO:0030007]; cellular response to amyloid-beta [GO:1904646]; cellular response to steroid hormone stimulus [GO:0071383]; cellular sodium ion homeostasis [GO:0006883]; neuron pro...
cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular potassium ion homeostasis [GO:0030007]; cellular response to amyloid-beta [GO:1904646]; cellular response to steroid hormone stimulus [GO:0071383]; cellular sodium ion homeostasis [GO:0006883]; neuron projection maintenance [GO:1990535]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; regulation of resting membrane potential [GO:0060075]; response to glycoside [GO:1903416]; sodium ion export across plasma membrane [GO:0036376]
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GO - Molecular function (MF):
amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chaperone binding [GO:0051087]; ion antiporter activity involved in regulation of presynaptic membrane potential [GO:0099520]; metal ion binding [GO:0046872]; P-type sodium:potassium-exchanging transpo...
amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; ATP hydrolysis activity [GO:0016887]; chaperone binding [GO:0051087]; ion antiporter activity involved in regulation of presynaptic membrane potential [GO:0099520]; metal ion binding [GO:0046872]; P-type sodium:potassium-exchanging transporter activity [GO:0005391]; steroid hormone binding [GO:1990239]
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GO - Cellular component (CC):
axon [GO:0030424]; endoplasmic reticulum [GO:0005783]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuronal cell body membrane [GO:0032809]; neuron to neuron synapse [GO:0098984...
axon [GO:0030424]; endoplasmic reticulum [GO:0005783]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuronal cell body membrane [GO:0032809]; neuron to neuron synapse [GO:0098984]; organelle membrane [GO:0031090]; photoreceptor inner segment [GO:0001917]; photoreceptor inner segment membrane [GO:0060342]; plasma membrane [GO:0005886]; sodium:potassium-exchanging ATPase complex [GO:0005890]; synapse [GO:0045202]
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ATP1A3
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Kaplan plot for ATP1A3 in
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*NOTE: the Kaplan plots were collected from OncoLnc