DegronMD - P13693(TPT1)

TPT1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H10L	TCGA-ZP-A9D0	LIHC	TCGA	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.2222
p.L7F	DO230322	COCA	ICGC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.3056
p.F2L	DO222884	COCA	ICGC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.6981
p.R9L	DO14278	HNSC	ICGC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation blocking phosphorylation signal	0.6944
p.R9L	DO39046	THCA	ICGC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation blocking phosphorylation signal	0.6944
p.A12E	DO228948	LICA	ICGC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation rewiring degron network	0.1667
p.R4G	ACH-000988	Endometrial/Uterine Cancer	CCLE	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7568
p.R4G	MFE-319	endometrium	COSMIC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7568
p.V2I	ACH-000999	Colon/Colorectal Cancer	CCLE	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7076
p.V2I	SNU-1040	large intestine	COSMIC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7076
p.E6K	ACH-002097	Skin Cancer	CCLE	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7022
p.E6K	CP66-MEL	skin	COSMIC	MIIYRD	LIG_APCC_ABBA_1	1:6	Mutation altering degron motif	0.7022

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*NOTE: the Kaplan plots were collected from OncoLnc