DegronMD - P13984(GTF2F2)

GTF2F2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G90E	TCGA-22-5481	LUSC	TCGA	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.25
p.G90E	DO27160	LUSC	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.25
p.S99I	TCGA-AX-A06F	UCEC	TCGA	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.3056
p.S99I	DO41752	UCEC	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.3056
p.L104P	TCGA-EY-A5W2	UCEC	TCGA	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.1667
p.L104P	DO48177	UCEC	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.1667
p.E98K	DO223057	ESCA	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation altering degron motif	0.7022
p.T92S	DO233169	GACA	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.3056
p.V84F	DO229018	LICA	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation rewiring degron network	0.0833
p.S87I	DO229035	LICA	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation blocking phosphorylation signal	0.6111
p.E98D	DO229068	PRAD	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation altering degron motif	0.5647
p.K103N	DO229268	THCA	ICGC	LTVFTE	LIG_APCC_ABBA_1	93:98	Mutation substituting flanking lysine	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc