DegronMD - P14866(HNRNPL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E341K	TCGA-C5-A1MI	CESC	TCGA	PPHY	ITCH	337:340	Mutation rewiring degron network	0.3056
p.M345I	TCGA-FS-A1ZQ	SKCM	TCGA	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1944
p.M345I	ACH-000717	Esophageal Cancer	CCLE	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1944
p.S331L	DO2401	BRCA	ICGC	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1667
p.R348Q	DO22920	LIHC	ICGC	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1111
p.R348W	DO38607	STAD	ICGC	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1111
p.S345G	DO40804	UCEC	ICGC	PPHY	ITCH	337:340	Mutation rewiring degron network	0.1944
p.P335A	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PPHY	ITCH	337:340	Mutation rewiring degron network	0.2778
p.P335A	ACH-000995	Leukemia	CCLE	PPHY	ITCH	337:340	Mutation rewiring degron network	0.2778
p.P338A	SIDM00047	Non-Small Cell Lung Carcinoma	GDSC	PPHY	ITCH	337:340	Mutation altering degron motif	0.7503
p.H339Y	SIDM01624	Bladder Carcinoma	GDSC	PPHY	ITCH	337:340	Mutation altering degron motif	0.6118
p.H339Y	ACH-000026	Bladder Cancer	CCLE	PPHY	ITCH	337:340	Mutation altering degron motif	0.6118

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons