DegronMD - P15144(ANPEP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N40K	TCGA-51-6867	LUSC	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1667
p.N40K	DO26477	LUSC	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1667
p.T57A	TCGA-55-7994	LUAD	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1389
p.T57A	DO45311	LUAD	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1389
p.P51L	TCGA-AJ-A3BH	UCEC	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P51L	TCGA-XF-AAMY	BLCA	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P51L	DO219050	BLCA	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P51L	DO41638	UCEC	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.S52P	TCGA-AP-A1DK	UCEC	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.2778
p.S52P	DO42033	UCEC	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.2778
p.P45L	TCGA-D9-A6EA	SKCM	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P45L	DO220906	MELA	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P45L	DO50290	SKCM	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P51S	TCGA-FR-A726	SKCM	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.P51S	DO48665	SKCM	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.3056
p.T57I	TCGA-YL-A8SR	PRAD	TCGA	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1389
p.T57I	DO51439	PRAD	ICGC	VASTT	DEG_SPOP_SBC_1	46:50	Mutation rewiring degron network	0.1389

Kaplan plot for ANPEP in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ANPEP

UniProt ID: P15144

Entrez ID: 290

Protein name: Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ANPEP in