DegronMD - P15289(ARSA)

ARSA

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V109M	TCGA-2W-A8YY	CESC	TCGA	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.2222
p.A123T	TCGA-AJ-A3BH	UCEC	TCGA	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.2778
p.G131V	TCGA-OR-A5KB	ACC	TCGA	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.0556
p.E131K	DO49802	BLCA	ICGC	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.0556
p.V107M	DO223732	CESC	ICGC	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.1667
p.A121T	DO41638	UCEC	ICGC	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation altering degron motif	0.6028
p.G129V	ACH-001111	Lymphoma	CCLE	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation rewiring degron network	0.1111
p.A114V	ACH-001649	Prostate Cancer	CCLE	ARGYLTGMA	DEG_APCC_DBOX_1	113:121	Mutation altering degron motif	0.6936

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*NOTE: the Kaplan plots were collected from OncoLnc