DegronMD - P16219(ACADS)

ACADS

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T219M	TCGA-5M-AAT6	COAD	TCGA	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation altering degron motif	0.8534
p.K227T	TCGA-UY-A78K	BLCA	TCGA	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation substituting flanking lysine	0.3333
p.K223T	DO219031	BLCA	ICGC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation altering degron motif	0.7306
p.T215M	DO223703	COAD	ICGC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation rewiring degron network	0.3056
p.T215M	DO233898	GACA	ICGC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation rewiring degron network	0.3056
p.G221R	DO228139	PBCA	ICGC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation altering degron motif	0.6457
p.R230L	DO229410	PRAD	ICGC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation substituting flanking lysine	0.25
p.M217I	SIDM01619	Endometrial Carcinoma	GDSC	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation altering degron motif	0.6507
p.M217I	ACH-000984	Endometrial/Uterine Cancer	CCLE	PMPTPGLT	DEG_SCF_FBW7_1	216:223	Mutation altering degron motif	0.6507

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*NOTE: the Kaplan plots were collected from OncoLnc