DegronMD - P17014(ZNF12)

ZNF12

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E112K	TCGA-17-Z026	LUAD	TCGA	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.1944
p.I92L	TCGA-AG-4009	READ	TCGA	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.0833
p.I92L	DO36961	READ	ICGC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.0833
p.N115D	TCGA-BG-A222	UCEC	TCGA	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.1111
p.P99H	TCGA-DU-6392	LGG	TCGA	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.2778
p.P99H	DO22237	LGG	ICGC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.2778
p.P99T	DO229037	LICA	ICGC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.2778
p.E107K	DO231040	LUSC	ICGC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation altering degron motif	0.7022
p.T103I	DO232761	PBCA	ICGC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation altering degron motif	0.5966
p.T103I	SIDM00660	Colorectal Carcinoma	GDSC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation altering degron motif	0.5966
p.T103I	LS-411N	large intestine	COSMIC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation altering degron motif	0.5966
p.T108A	VMRC-MELG	skin	COSMIC	RQTVFIE	LIG_APCC_ABBAyCdc20_2	101:107	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc