ADRA2C
UniProt ID: P18825
Entrez ID: 152
Protein name: Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins....
FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
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GO - Biological processes (BP):
activation of protein kinase B activity [GO:0032148]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation ...
activation of protein kinase B activity [GO:0032148]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of norepinephrine secretion [GO:0010700]; platelet activation [GO:0030168]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; receptor transactivation [GO:0035624]; regulation of smooth muscle contraction [GO:0006940]; regulation of vasoconstriction [GO:0019229]
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GO - Molecular function (MF):
alpha-2A adrenergic receptor binding [GO:0031694]; alpha2-adrenergic receptor activity [GO:0004938]; epinephrine binding [GO:0051379]; G protein-coupled receptor activity [GO:0004930]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]...
alpha-2A adrenergic receptor binding [GO:0031694]; alpha2-adrenergic receptor activity [GO:0004938]; epinephrine binding [GO:0051379]; G protein-coupled receptor activity [GO:0004930]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
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GO - Cellular component (CC):
cytoplasm [GO:0005737]; endosome [GO:0005768]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]...
cytoplasm [GO:0005737]; endosome [GO:0005768]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]
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ADRA2C
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Kaplan plot for ADRA2C in
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*NOTE: the Kaplan plots were collected from OncoLnc