DegronMD - P21217(FUT3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P75S	TCGA-21-1079	LUSC	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.P75S	TCGA-D3-A51T	SKCM	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.P75S	DO26846	LUSC	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.P75S	DO47389	SKCM	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.S51Y	TCGA-AG-3602	READ	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.S51Y	DO36994	READ	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1111
p.T56I	TCGA-AP-A059	UCEC	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.25
p.T56I	DO41361	UCEC	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.25
p.L63F	TCGA-BF-AAP4	SKCM	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6981
p.L63F	DO219468	SKCM	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6981
p.L67I	TCGA-BS-A0UF	UCEC	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6063
p.L67I	DO41488	UCEC	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6063
p.R60C	TCGA-CI-6621	READ	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.8301
p.R60C	DO36970	READ	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.8301
p.R60C	SIDM01175	Other Sarcomas	GDSC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.8301
p.R60C	SW684	soft tissue	COSMIC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.8301
p.Q54H	TCGA-EE-A2MD	SKCM	TCGA	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.Q54H	DO222434	MELA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.Q54H	DO37851	SKCM	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.R60H	DO222960	BTCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.8244
p.T59P	DO222842	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5919
p.T59P	DO229218	THCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5919
p.R68W	DO229010	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.R68W	DO229013	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.R68W	DO229016	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.R68W	DO229003	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.R68W	DO229005	COCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.3056
p.P61R	DO51001	LAML	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6401
p.Q54K	DO228971	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation rewiring degron network	0.1944
p.T59N	DO229018	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.T59N	DO229029	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.T59N	DO229032	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.T59N	DO229037	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.T59N	DO229006	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.T59N	DO229009	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5944
p.R60S	DO229018	LICA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.7427
p.P61L	DO46823	RECA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.6471
p.T62P	DO218874	SKCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.5919
p.R60P	DO229218	THCA	ICGC	TRPTLLILL	DEG_APCC_DBOX_1	59:67	Mutation altering degron motif	0.7512

Kaplan plot for FUT3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FUT3

UniProt ID: P21217

Entrez ID: 2525

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FUT3 in