DegronMD - P22314(UBA1)

UBA1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R1058C	TCGA-A5-A1OF	UCEC	TCGA	TIR	DEG_APCC_TPR_1	1056:1058	Mutation altering degron motif	0.8301
p.R1058C	DO42568	UCEC	ICGC	TIR	DEG_APCC_TPR_1	1056:1058	Mutation altering degron motif	0.8301
p.R1058S	TCGA-AP-A059	UCEC	TCGA	TIR	DEG_APCC_TPR_1	1056:1058	Mutation altering degron motif	0.7427
p.R1058S	DO41361	UCEC	ICGC	TIR	DEG_APCC_TPR_1	1056:1058	Mutation altering degron motif	0.7427
p.E1046K	SIDM00596	Endometrial Carcinoma	GDSC	TIR	DEG_APCC_TPR_1	1056:1058	Mutation rewiring degron network	0.0556
p.E1046K	ACH-000941	Endometrial/Uterine Cancer	CCLE	TIR	DEG_APCC_TPR_1	1056:1058	Mutation rewiring degron network	0.0556
p.E1046K	ACH-000954	Endometrial/Uterine Cancer	CCLE	TIR	DEG_APCC_TPR_1	1056:1058	Mutation rewiring degron network	0.0556
p.E1046K	ACH-001517	Endometrial/Uterine Cancer	CCLE	TIR	DEG_APCC_TPR_1	1056:1058	Mutation rewiring degron network	0.0556
p.E1046K	HEC-1	endometrium	COSMIC	TIR	DEG_APCC_TPR_1	1056:1058	Mutation rewiring degron network	0.0556

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc