DegronMD - P22794(EVI2A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F39L	TCGA-61-2009	OV	TCGA	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.6981
p.E29K	TCGA-BR-7901	STAD	TCGA	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation substituting flanking lysine	0.2222
p.E29G	TCGA-BS-A0UV	UCEC	TCGA	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation substituting flanking lysine	0.2222
p.L40M	TCGA-DU-6392	LGG	TCGA	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.711
p.T42A	TCGA-XK-AAIW	PRAD	TCGA	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.3056
p.Q48E	DO51639	CESC	ICGC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.1389
p.N31K	DO229045	LICA	ICGC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.1667
p.N31K	DO41133	UCEC	ICGC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.1667
p.I47T	DO223720	LUSC	ICGC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.1667
p.G27E	DO27851	MALY	ICGC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0556
p.Y34C	SIDM02021	Esophageal Carcinoma	GDSC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.H36R	SIDM00078	Oral Cavity Carcinoma	GDSC	ANSTS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons