DegronMD - P23229(ITGA6)

ITGA6

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G827E	TCGA-18-3409	LUSC	TCGA	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation altering degron motif	0.7199
p.E817K	TCGA-2W-A8YY	CESC	TCGA	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.2222
p.E817K	TCGA-AX-A2HC	UCEC	TCGA	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.2222
p.Q818K	TCGA-A4-7734	KIRP	TCGA	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.25
p.L831V	DO51918	BLCA	ICGC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation altering degron motif	0.6765
p.S839L	DO566	BLCA	ICGC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.1944
p.P821L	DO3406	BRCA	ICGC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation altering degron motif	0.7582
p.S816G	DO228308	MALY	ICGC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.1944
p.I837T	SIDM00878	Breast Carcinoma	GDSC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.25
p.I837T	ACH-000930	Breast Cancer	CCLE	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.25
p.I837T	HCC1569	breast	COSMIC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.25
p.I832T	HCC1569	breast	COSMIC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation altering degron motif	0.7078
p.G842V	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.1111
p.N817S	CHSA0108	bone	COSMIC	LAPITAKAKVVIEL	DEG_ODPH_VHL_1	821:834	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc