DegronMD - P23582(NPPC)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P35S	DO50970	LICA	ICGC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation altering degron motif	0.6752
p.A27V	DO229192	THCA	ICGC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.2222
p.A41T	DO229218	THCA	ICGC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.25
p.P36Q	DO229227	THCA	ICGC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation altering degron motif	0.5924
p.Q44R	SIDM00305	Ovarian Carcinoma	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.Q44R	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.Q44R	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.Q44R	SIDM01368	Gastric Carcinoma	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.Q44R	SIDM01658	Unknown	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.Q44R	SIDM01762	Esophageal Squamous Cell Carcinoma	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.1667
p.A27S	SIDM00287	B-Lymphoblastic Leukemia	GDSC	VPRTPPAE	DEG_SCF_FBW7_2	31:38	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons