DegronMD - P24386(CHM)

CHM

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M196V	TCGA-33-AASJ	LUSC	TCGA	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.M196V	DO219131	LUSC	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.D184G	TCGA-55-8301	LUAD	TCGA	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.D184G	DO24682	LUAD	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.S197G	TCGA-62-A471	LUAD	TCGA	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.1944
p.S197G	DO45347	LUAD	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.1944
p.M196I	TCGA-66-2734	LUSC	TCGA	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.M196I	DO26430	LUSC	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.2222
p.D195E	DO229019	LICA	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.25
p.D195E	DO229029	LICA	ICGC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation rewiring degron network	0.25
p.P189T	SIDM00554	Ovarian Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation altering degron motif	0.5919
p.P189T	ACH-000524	Ovarian Cancer	CCLE	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation altering degron motif	0.5919
p.P189T	KURAMOCHI	ovary	COSMIC	VPSTS	DEG_SPOP_SBC_1	188:192	Mutation altering degron motif	0.5919

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*NOTE: the Kaplan plots were collected from OncoLnc