PTX3
UniProt ID: P26022
Entrez ID: 5806
Protein name: Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. {ECO:0000305|PubMed:12763682}....
FUNCTION: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. {ECO:0000305|PubMed:12763682}.
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GO - Biological processes (BP):
extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulati...
extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation by host of viral process [GO:0044793]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of viral entry into host cell [GO:0046597]; opsonization [GO:0008228]; ovarian cumulus expansion [GO:0001550]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phagocytosis [GO:0050766]; response to yeast [GO:0001878]
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GO - Molecular function (MF):
(1->3)-beta-D-glucan binding [GO:0001872]; complement component C1q complex binding [GO:0001849]; identical protein binding [GO:0042802]; virion binding [GO:0046790]...
(1->3)-beta-D-glucan binding [GO:0001872]; complement component C1q complex binding [GO:0001849]; identical protein binding [GO:0042802]; virion binding [GO:0046790]
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GO - Cellular component (CC):
extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]...
extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]
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PTX3
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Kaplan plot for PTX3 in
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*NOTE: the Kaplan plots were collected from OncoLnc