DegronMD - P28289(TMOD1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K221N	TCGA-AX-A05Z	UCEC	TCGA	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation altering degron motif	0.6918
p.K221N	DO40884	UCEC	ICGC	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation altering degron motif	0.6918
p.L220P	TCGA-HU-A4GT	STAD	TCGA	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation altering degron motif	0.6471
p.L220P	DO48020	STAD	ICGC	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation altering degron motif	0.6471
p.G233V	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation rewiring degron network	0.0833
p.G233V	ACH-002272	Lymphoma	CCLE	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation rewiring degron network	0.0833
p.G233V	MHH-PREB-1	haematopoietic and lymphoid tissue	COSMIC	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation rewiring degron network	0.0833
p.V212L	MC-IXC	autonomic ganglia	COSMIC	LKENS	DEG_APCC_KENBOX_2	220:224	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons