DegronMD - P28698(MZF1)

MZF1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E164Q	TCGA-08-0386	GBM	TCGA	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.25
p.E164Q	DO13504	GBM	ICGC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.25
p.P171S	TCGA-AP-A1DK	UCEC	TCGA	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5641
p.P171S	DO42033	UCEC	ICGC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5641
p.P161Q	TCGA-EE-A181	SKCM	TCGA	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.1667
p.P161Q	DO37444	SKCM	ICGC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.1667
p.P165S	TCGA-EY-A215	UCEC	TCGA	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.2778
p.P165S	DO42665	UCEC	ICGC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.2778
p.Q182K	DO229031	LICA	ICGC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation rewiring degron network	0.0833
p.T162S	SIDM00721	Small Cell Lung Carcinoma	GDSC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation blocking phosphorylation signal	0.6389
p.K168N	SIDM00959	Acute Myeloid Leukemia	GDSC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5806
p.K168N	ACH-000641	Leukemia	CCLE	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5806
p.K168N	ACH-001036	Leukemia	CCLE	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5806
p.K168N	CMK	haematopoietic and lymphoid tissue	COSMIC	PKTPPRT	DEG_SCF_FBW7_1	167:173	Mutation altering degron motif	0.5806

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*NOTE: the Kaplan plots were collected from OncoLnc