DegronMD - P29375(KDM5A)

KDM5A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A1361G	TCGA-A8-A0AB	BRCA	TCGA	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.2778
p.A1361G	DO5877	BRCA	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.2778
p.E1377V	TCGA-CK-4951	COAD	TCGA	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.0556
p.E1377V	DO10582	COAD	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.0556
p.E1377V	DO233298	NACA	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.0556
p.P1371S	TCGA-CV-6003	HNSC	TCGA	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.2222
p.P1371S	DO15639	HNSC	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.2222
p.S1366A	TCGA-Z2-A8RT	SKCM	TCGA	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation altering degron motif	0.7588
p.S1366A	DO51301	SKCM	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation altering degron motif	0.7588
p.D1359G	DO222884	COCA	ICGC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.2222
p.L1373P	SIDM02029	Colorectal Carcinoma	GDSC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.1667
p.L1373V	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.1667
p.L1373V	H513	pleura	COSMIC	VKSSS	DEG_SPOP_SBC_1	1363:1367	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc