DegronMD - P30304(CDC25A)

CDC25A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P154T	TCGA-AX-A06F	UCEC	TCGA	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.0556
p.P154T	DO41752	UCEC	ICGC	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.0556
p.F148L	TCGA-CK-4951	COAD	TCGA	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.2222
p.F148L	DO10582	COAD	ICGC	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.2222
p.E139D	TCGA-FT-A3EE	BLCA	TCGA	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.3056
p.E139D	DO720	BLCA	ICGC	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.3056
p.D130G	SIDM01307	Colorectal Carcinoma	GDSC	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.0556
p.I131V	SIDM00176	Chondrosarcoma	GDSC	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.0833
p.A145D	ACH-001422	Prostate Cancer	CCLE	NKENE	DEG_APCC_KENBOX_2	140:144	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc