DegronMD - P31785(IL2RG)

IL2RG

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E368K	TCGA-17-Z022	LUAD	TCGA	PPCY	ITCH	360:363	Mutation rewiring degron network	0.1944
p.A359P	TCGA-BR-6452	STAD	TCGA	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	DO225337	BRCA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	DO233869	GACA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	DO233944	GACA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	DO38404	STAD	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	SIDM01424	B-Lymphoblastic Leukemia	GDSC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	ACH-000782	Leukemia	CCLE	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.A359P	ACH-001735	Leukemia	CCLE	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056
p.P361S	TCGA-EM-A4FM	THCA	TCGA	PPCY	ITCH	360:363	Mutation altering degron motif	0.6752
p.P361S	DO48088	THCA	ICGC	PPCY	ITCH	360:363	Mutation altering degron motif	0.6752
p.T369I	DO224684	BRCA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.1667
p.P367T	DO228948	LICA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.2222
p.S355R	DO228952	LICA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.1944
p.A359D	DO229041	LICA	ICGC	PPCY	ITCH	360:363	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc