DegronMD

Uniprot ID: P31785

Source protein: Cytokine receptor common subunit gamma

Source gene: IL2RG

Class: ITCH

Location: 360:363

E3 ligase: ITCH,NEDD4

DEGRON score: 0.9947

ASA_SCORE: 85.6

COIL: 0.902

CONS_SCORE: 0.3908

DSS_SCORE: 0.4609

HELIX: 0.0347

FCONS_SCORE: 1.0028

RIG_SCORE: 0.7764

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O95996	Adenomatous polyposis coli protein 2	ITCH	1574:1577	PPCY	ITCH,NEDD4	0.9736	More...
P31785	Cytokine receptor common subunit gamma	ITCH	360:363	PPCY	ITCH,NEDD4	0.9947	More...
Q9GZS1	DNA-directed RNA polymerase I subunit RPA49	ITCH	201:204	PPCY	ITCH,NEDD4	0.994	More...
Q9H3M7	Thioredoxin-interacting protein	ITCH	331:334	PPCY	ITCH,NEDD4	0.9982	More...
Q9ULL8	Protein Shroom4	ITCH	1232:1235	PPCY	ITCH,NEDD4	0.9603	More...
Q8WV15	Transmembrane protein 255B	ITCH	307:310	PPCY	ITCH,NEDD4	0.9924	More...
Q9H425	Uncharacterized protein C1orf198	ITCH	226:229	PPCY	ITCH,NEDD4	0.9312	More...
Q8N4L1	Transmembrane protein 151A	ITCH	440:443	PPCY	ITCH,NEDD4	0.9955	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons