DegronMD - Q9H425(C1orf198)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D237Y	TCGA-37-3783	LUSC	TCGA	PPCY	ITCH	226:229	Mutation rewiring degron network	0.1111
p.S217F	TCGA-AX-A0J1	UCEC	TCGA	PPCY	ITCH	226:229	Mutation rewiring degron network	0.0833
p.P235L	TCGA-BR-4363	STAD	TCGA	PPCY	ITCH	226:229	Mutation rewiring degron network	0.1667
p.P233S	TCGA-ER-A2ND	SKCM	TCGA	PPCY	ITCH	226:229	Mutation rewiring degron network	0.2222
p.R224H	DO233872	GACA	ICGC	PPCY	ITCH	226:229	Mutation rewiring degron network	0.2778
p.R224H	DO37433	SKCM	ICGC	PPCY	ITCH	226:229	Mutation rewiring degron network	0.2778
p.S234G	DO229047	LICA	ICGC	PPCY	ITCH	226:229	Mutation rewiring degron network	0.1944
p.N219S	DO50807	LIRI	ICGC	PPCY	ITCH	226:229	Mutation rewiring degron network	0.1389
p.R226S	DO29800	OV	ICGC	PPCY	ITCH	226:229	Mutation altering degron motif	0.7427
p.E223K	DO41903	UCEC	ICGC	PPCY	ITCH	226:229	Mutation substituting flanking lysine	0.3611
p.R230W	SIDM00685	Glioblastoma	GDSC	PPCY	ITCH	226:229	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons