DegronMD - P31943(HNRNPH1)

HNRNPH1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P311L	DO233731	GACA	ICGC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation rewiring degron network	0.2222
p.P311L	DO233903	GACA	ICGC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation rewiring degron network	0.2222
p.H318Q	DO228986	LICA	ICGC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation altering degron motif	0.7582
p.H318Q	DO229027	LICA	ICGC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation altering degron motif	0.7582
p.Y306D	DO23240	LINC	ICGC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation blocking phosphorylation signal	0.5278
p.I321S	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation rewiring degron network	0.3056
p.I321S	ACH-000562	Lung Cancer	CCLE	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation rewiring degron network	0.3056
p.I321S	HCC-78	lung	COSMIC	VRVHIE	LIG_APCC_ABBA_1	315:320	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc