GTF2F1
UniProt ID: P35269
Entrez ID: 2962
Protein name: General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}....
FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}.
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GO - Biological processes (BP):
negative regulation of protein binding [GO:0032091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; response to virus [GO:0009615]; transcription by RNA polymerase II [GO:0006366]; ...
negative regulation of protein binding [GO:0032091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; response to virus [GO:0009615]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]
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GO - Molecular function (MF):
DNA binding [GO:0003677]; phosphatase activator activity [GO:0019211]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activit...
DNA binding [GO:0003677]; phosphatase activator activity [GO:0019211]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; TFIIF-class transcription factor complex binding [GO:0001096]
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GO - Cellular component (CC):
cell junction [GO:0030054]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIF complex [GO:0005674]...
cell junction [GO:0030054]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIF complex [GO:0005674]
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GTF2F1
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Kaplan plot for GTF2F1 in
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*NOTE: the Kaplan plots were collected from OncoLnc