DegronMD - P35408(PTGER4)

PTGER4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G408S	TCGA-04-1342	OV	TCGA	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.25
p.G408S	DO29548	OV	ICGC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.25
p.G408D	TCGA-B5-A3FC	UCEC	TCGA	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.25
p.G408D	DO41871	UCEC	ICGC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.25
p.N413H	TCGA-BR-7196	STAD	TCGA	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.6312
p.N413H	DO38235	STAD	ICGC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation altering degron motif	0.6312
p.L401V	TCGA-HU-8238	STAD	TCGA	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0556
p.L401V	DO47944	STAD	ICGC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0556
p.A424T	DO233697	GACA	ICGC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.1944
p.T428P	SIDM01525	Acute Myeloid Leukemia	GDSC	GRNLLPGVP	DEG_APCC_DBOX_1	411:419	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc