DegronMD - P36957(DLST)

DLST

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P116Q	TCGA-14-1794	GBM	TCGA	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.7035
p.T111P	TCGA-2W-A8YY	CESC	TCGA	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.5919
p.E99K	TCGA-A1-A0SI	BRCA	TCGA	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation rewiring degron network	0.1111
p.E99K	DO1774	BRCA	ICGC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation rewiring degron network	0.1111
p.S112Y	TCGA-AP-A059	UCEC	TCGA	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.6009
p.S112Y	DO41361	UCEC	ICGC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.6009
p.I123T	TCGA-D1-A17Q	UCEC	TCGA	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation rewiring degron network	0.1944
p.Q97H	DO447	BLCA	ICGC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation rewiring degron network	0.0556
p.V102A	DO232224	PBCA	ICGC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation rewiring degron network	0.1944
p.S114Y	DO41572	UCEC	ICGC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.712
p.E107A	SIDM01272	Colorectal Carcinoma	GDSC	ETDKTSVQVPSP	DEG_COP1_1	107:118	Mutation altering degron motif	0.7701

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*NOTE: the Kaplan plots were collected from OncoLnc