DegronMD - P40855(PEX19)

PEX19

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A44T	TCGA-AL-3473	KIRP	TCGA	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2778
p.A44T	DO20905	KIRP	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2778
p.P39S	TCGA-D3-A1Q9	SKCM	TCGA	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.5641
p.P39S	DO37428	SKCM	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.5641
p.A37S	TCGA-DF-A2KS	UCEC	TCGA	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.A37S	DO223285	UCEC	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.S40F	TCGA-K4-A3WS	BLCA	TCGA	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.9093
p.S40F	DO480	BLCA	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.9093
p.T43K	DO229027	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.T43K	DO229036	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.S40Y	DO229036	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.8231
p.T42N	DO229035	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.8166
p.P50L	SIDM00081	Melanoma	GDSC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.P50L	ACH-000615	Skin Cancer	CCLE	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.P50L	SK-MEL-28	skin	COSMIC	PPSTT	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc