DegronMD - P41227(NAA10)

NAA10

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D208E	TCGA-25-2404	OV	TCGA	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation altering degron motif	0.5647
p.G199C	TCGA-D3-A1QA	SKCM	TCGA	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.1944
p.T218I	TCGA-EY-A1GK	UCEC	TCGA	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.0833
p.E196K	TCGA-EY-A549	UCEC	TCGA	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.1111
p.D208G	TCGA-HT-A616	LGG	TCGA	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation altering degron motif	0.6087
p.D208G	NCI-H2141	lung	COSMIC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation altering degron motif	0.6087
p.E199K	DO222973	BTCA	ICGC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.1944
p.D217N	DO233855	GACA	ICGC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.1111
p.S212I	DO16023	HNSC	ICGC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.25
p.D208H	DO26560	LUSC	ICGC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation altering degron motif	0.6577
p.T203I	DO42985	UCEC	ICGC	DSGGDS	DEG_SCF_TRCP1_1	204:209	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc