DegronMD - P41236(PPP1R2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E70K	TCGA-77-8136	LUSC	TCGA	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.3056
p.E70K	DO26593	LUSC	ICGC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.3056
p.A85V	TCGA-AD-5900	COAD	TCGA	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.1111
p.A85V	DO8514	COAD	ICGC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.1111
p.A85T	DO223048	ESCA	ICGC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.1111
p.D69G	DO44875	LIHC	ICGC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.2778
p.M79T	SIDM00264	Ewing's Sarcoma	GDSC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.2778
p.M79T	ACH-002105	Bone Cancer	CCLE	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.2778
p.M79T	ES4	bone	COSMIC	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.2778
p.M78I	ACH-000961	Endometrial/Uterine Cancer	CCLE	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.3056
p.A85S	ACH-001510	Head and Neck Cancer	CCLE	PSTPYHS	DEG_SCF_FBW7_1	71:77	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons