DegronMD - P43351(RAD52)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V277I	TCGA-B5-A11J	UCEC	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.2778
p.P292R	TCGA-BA-A6DJ	HNSC	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1389
p.S287G	TCGA-CG-5723	STAD	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation blocking phosphorylation signal	0.7222
p.E285Q	TCGA-DK-A1AB	BLCA	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation altering degron motif	0.6744
p.E285D	TCGA-EE-A2GI	SKCM	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation altering degron motif	0.6758
p.R269W	TCGA-FC-A4JI	PRAD	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.0556
p.A293S	TCGA-FS-A1ZG	SKCM	TCGA	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1111
p.R269Q	DO474	BLCA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.0556
p.T289I	DO233276	GACA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.2222
p.H295N	DO229018	LICA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.0556
p.N285K	DO229019	LICA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation altering degron motif	0.6918
p.N291K	DO229015	LICA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1667
p.A282D	DO229028	LICA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation altering degron motif	0.7793
p.Q286K	DO44832	LICA	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.3056
p.Q290H	DO25613	LUAD	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1944
p.T277I	DO46591	OV	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.2778
p.P286L	DO49762	PRAD	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.3056
p.A272T	DO51776	STAD	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1389
p.A272T	DO38328	STAD	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1389
p.G294D	DO43698	UCEC	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.0833
p.P294S	DO41235	UCEC	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.0833
p.R292M	DO41235	UCEC	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.1389
p.A278T	DO43891	UCEC	ICGC	VSTPSAE	DEG_SCF_FBW7_2	279:285	Mutation rewiring degron network	0.3056

Kaplan plot for RAD52 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RAD52

UniProt ID: P43351

Entrez ID: 5893

Protein name: DNA repair protein RAD52 homolog

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for RAD52 in