DegronMD - P43358(MAGEA4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q29K	TCGA-44-6774	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.Q29K	DO25000	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.A39S	TCGA-50-5946	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7588
p.A39S	DO24556	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7588
p.E52K	TCGA-A2-A0YK	BRCA	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.E52K	DO2836	BRCA	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.P45S	TCGA-FR-A7UA	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778
p.P45S	DO51253	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778
p.E53K	TCGA-FS-A1ZZ	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.E53K	DO222420	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.E53K	DO222753	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.E53K	DO222843	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.E53K	DO37412	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.E34K	TCGA-G2-AA3B	BLCA	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1944
p.E34K	DO51882	BLCA	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1944
p.L46V	TCGA-RY-A83Z	LGG	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.25
p.L46V	DO219839	LGG	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.25
p.P48T	TCGA-XK-AAIW	PRAD	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1944
p.P48T	DO51407	PRAD	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1944
p.S43F	TCGA-YG-AA3N	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7982
p.S43F	DO51298	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7982
p.S43F	ACH-001302	Neuroblastoma	CCLE	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7982
p.P31A	DO231169	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.P31S	SIDM00621	Ewing's Sarcoma	GDSC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.P45H	SIDM00863	Burkitt's Lymphoma	GDSC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778
p.P45H	ACH-001064	Lymphoma	CCLE	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778
p.P45H	EB2	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778

Kaplan plot for MAGEA4 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAGEA4

UniProt ID: P43358

Entrez ID: 4103

Protein name: Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAGEA4 in