DegronMD - P46695(IER3)

IER3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S31F	DO222498	MELA	ICGC	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation blocking phosphorylation signal	0.5278
p.T23I	DO32831	PACA	ICGC	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation rewiring degron network	0.3056
p.A16D	SIDM01112	Osteosarcoma	GDSC	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation rewiring degron network	0.3056
p.G32S	SIDM01121	Small Cell Lung Carcinoma	GDSC	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation rewiring degron network	0.0556
p.S22P	SIDM01608	Endometrial Carcinoma	GDSC	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation altering degron motif	0.6752
p.R28W	ACH-000889	Myeloma	CCLE	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation rewiring degron network	0.1667
p.P9Q	ACH-000911	Gastric Cancer	CCLE	PTPAPS	DEG_SCF_FBW7_1	17:22	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc