DegronMD - P47211(GALR1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T340I	TCGA-L4-A4E5	LUAD	TCGA	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation altering degron motif	0.7078
p.T340I	DO24320	LUAD	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation altering degron motif	0.7078
p.S334N	DO229010	COCA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.S334N	DO229013	COCA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.S334N	DO229016	COCA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.S334N	DO229003	COCA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.S334N	DO229005	COCA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.D330N	DO220859	MELA	ICGC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.1111
p.V349A	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.1944
p.V349A	NCI-H1155	lung	COSMIC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.1944
p.P342L	SIDM00793	Burkitt's Lymphoma	GDSC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation altering degron motif	0.6471
p.H348Q	SIDM01689	B-Lymphoblastic Leukemia	GDSC	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222
p.H348Q	ACH-000492	Leukemia	CCLE	IDTPPST	DEG_SCF_FBW7_1	338:344	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons